Water

Water is used for rinsing and cleaning of filling jets, bottles, kegs or other containers. This water should be sterile, so that rinsing does not result in contamination.

Water is also very often part of the final process or even the final product itself. Therefore one must recognize the importance of the fine filtration of table or mineral waters, the sterile filtration or bacteria reduction of water intended for the addition to non-alcoholic drinks, juices, beer or syrup.

   Mixed water filtration

 Application  Process medium  Recommended ultrafilter system  Pore size
 Pre filtration  Water   Ultramesh P-Sm
 Ultrapolyplea P-PP 
 Ultrapolyplea P-PP100
 50-250 µm
 0.1-30-250 µm
 0.6-5 µm
 Final filtration  Water   ultrabev P-PF-BEV  0.2-0.45 µm

Water filtration

There are two relevant standards concerning the water quality for the pharmaceutical and biotechnology industry:

WFI. water for injection: This water meets the highest level of requirements. It is used for the adjustment of product concentration. for the production of WFI steam, and for the cleaning of ampoules or vials.

PW, purified water or deionizied water (DI-water) is mainly used for cleaning of bottles and ampoules or as a supply for fermenters. It is also an addition to lotions, creams and used in the production of purest steam for sterilization.

For the production of these water qualities ultrafilter offers the asymetrical polyethersulfone membrane with retention rates down to 40 Nanometers (= 0.04pm). This filter medium is characterized by substantially high flow rates and a low differential pressure.

Compared to traditional filter media the differential pressure is 4 to 8 times lower! For the end-user this means the highest safety at low filtration costs. Picture  l l shows a typical process of sterile water treatment.

 Filter no.  Application  Recommended ultra filter filter  Pore size
 1  Course particle retention   ultrapoluplea P-PP  30 µm
 2  Course particle retention  ultrapoluplea P-PP  10 - 30 µm
 3  Pyrogen reduction and fine
 particle retention
 ultrapoluplea P-PP
 ultrapoluplea P-PP100
 0.2-1 µm
 0.45-1.2 µm
 4  Sterile filtration of D!-water  ultrasulfomem P-PF-PES  0.2 µm
 5  Sterile aeration and
 de-aeration
 Venting
 ultradepth II P-BE
 ultrapolymem P-PF-PP
 ultrateflomem P-PF-PT
 0.01 µm up to 99.999%
 0.1 - 0.2 µm
 0.1 - 0.2 µm
 6  Sterile filter  ultrasulfomem P-PF-PES  0.04-0.2 µm
Typical applications for the sterile storage of dairy products are shown schematically in the following picture.

Tank venting and storage with laminar flow of sterile air
 Application  Process medium  Recommended ultra filter system  Pore size
 Purging of storage and
 mixing tanks with
 sterile air.
 Air  ultradepth P-SLF  0.01 µm at
 99.999%
 Venting of storage
 and mixing tanks
 Air  ultradepth II P-BE  0.01 µm at
 99.999%
     ultrapolymem P-PF-PP
 ultrapolymem P-PF-PT
 0.1 - 0.2 µm
 0.1 - 0.45 µm